Henderson Street is a street in Galesburg. It runs north-south, and marks the 800 block west.
The street runs from its northern end at an interchange with Highway 34 (north of which it is Highway 150 to its southern end at County Road 10. North Henderson is cosigned as Highway 150, after which Main Street leading east is cosigned.
North of Main Street it is called North Henderson Street, and south of Main Street it is called South Henderson Street.